Journal: Lipids in Health and Disease
Article Title: Germacrone suppresses renal cancer growth by regulating c-Fos-mediated lipid metabolism
doi: 10.1186/s12944-026-02927-0
Figure Lengend Snippet: Germacrone attenuated c-Fos dependent lipid biosynthesis in xenograft tumors. A Immunohistochemistry analysis of c-Fos in tumor tissues (Scale bar = 50 μm). B BODIPY 493/503 (Scale bar = 20 μm), and ( C ) Oil Red O (Scale bar = 50 μm) staining on tumor frozen sections. D The relative cell viability of the NC, GER, PA, and PA + GER groups at 24, 48 and 72 h. E The intratumoral levels of total triglycerides and cholesterol were measured following germacrone administration. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001
Article Snippet: Oil Red O staining was implemented with the Modified Oil Red O Staining Kit (Beyotime, Jiangsu, China), as directed by the manufacturer.
Techniques: Immunohistochemistry, Staining